Currently Enrolling Clinical Trials - Updated March 15, 2011 Diabetic Neuropathy Multiple Sclerosis Parkinson's Disease Seizure Disorders and Epilepsy Parkinson's Disease Parkinson's disease trials offer medication to improve mobility and in some cases test medicine which may delay the progression of the condition. If you or someone you know is interested in enrolling, please use the form below. Type of Drug Phase Stage Add-On Placebo Duration Open Label Anti-hypotensive III Any Standard Therapy Yes 12 weeks Yes Antipsychotic III Any Standard Therapy Yes 12 weeks Yes Seizure Disorder and Epilepsy Epilepsy or Seizure Disorder is the tendency to have recurrent seizures. These trials offer medication or devices to reduce seizure frequency. In some cases they may also test an approach to delay the progression of the condition. If you or someone you know is interested in enrolling, please use the form below. For ethical reasons, trials which involve placebo are always Add-On, where a patient may receive a placebo (sugar pill) he or she will still be taking at least one anti-seizure medication. Type of Seizures Type of Drug Phase Add-On VNS Allowed Placebo Duration Open Label Partial Seizures Slow sodium-channel modulator III No No No 30 weeks Yes Partial Seizures Fast sodium-channel blocker III Yes Yes 33% 22 weeks 1 year Partial Seizures Fast sodium-channel blocker III No Yes No 18 weeks 1 year Partial Seizures Once daily fast sodium-channel blocker III Yes Yes 33% 35 weeks Yes Partial Seizures AMPA receptor blocker III Yes Yes 33% 25 weeks Yes Multiple Sclerosis Multiple sclerosis trials offer medication to reduce attack frequency. In some cases they may also test an approach to delay the progression of the condition. Others address symptoms like pain in MS. If you or someone you know is interested in enrolling, please use the form below. Subtype of MS Type of Drug Phase Add-On Placebo Duration Open Label Relapsing-Remitting Oral Immunomodulator III No 25% get standard therapy 6 months Yes Relapsing-Remitting Interferon plus Oral Immunomodulator III Yes 33% 24 months Yes First Clinical Episode Suggestive of MS Oral Immunomodulator III Yes 33% 24-30 months Yes Injectable 3x/wk Protein Immunomodulator III Yes 50% 6 months No Pain Associated with Diabetic Neuropathy Neuropathic pain is abnormal painful sensations, like burning or electrical jolts. New medication may reduce or even eliminate these sensations. If you or someone you know is interested in enrolling, please use the form below. Type of Drug Phase Add-On Placebo Duration Open Label α2δ-modulator III No 50% 4 months None Contact Us If you or a loved one is interested in participating in one of our trials, please contact us at (866) 829-1919 or use the form below. One of our skilled Clinical Research Coordinators will contact you as soon as possible. Thank you for your interest in our research! - Stephen S. Flitman, MD, Principal Investigator Your Name Name of Patient Your Telephone Best Time to Call Trial Type (please choose) General Inquiry --------------------- Alzheimer's Disease Parkinson's Disease Seizure Disorder or Epilepsy Fibromyalgia Migraine Multiple Sclerosis Diabetic Neuropathy Comments  Ready? If you are already a patient in the practice and need to reach the doctor on call, do not use this form; call 602-265-6500 directly

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